Enterprise Evidence Report · NR-REPORT-V2.0

Canada
Neuroscience Intelligence

Canada neuroscience evidence report: current clinical, research, institution and source-linked intelligence.

Evidence rank #5 of 50 · Data maturity A · Research score 50.9 · Data confidence 100.0 / 100 · Snapshot 2026-10-29 06:18 UTC.

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510Curated trials
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129Recruiting trials
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797Publications
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298Institutions

Executive interpretation

Canada ranks #5 in the current NeuroRisk evidence-ranked market layer. This ranking summarizes indexed clinical, publication and institution evidence; it is not a probability of commercial success and not an investment recommendation.

Methodology status

Methodology NR-REPORT-V2.0. Clinical metrics and NCT evidence use only records classified as in_scope or related; out_of_scope records remain preserved outside these analytical counts. No synthetic ML confidence is presented as scientific probability. Counts and source links below are tied to the generation snapshot.

Methodology →

Leading sponsors

Merck Sharp & Dohme LLC2611 recruiting
University of Calgary181 recruiting
Hoffmann-La Roche165 recruiting
Centre for Addiction and Mental Health144 recruiting
Sunnybrook Health Sciences Centre115 recruiting
Eli Lilly and Company100 recruiting
Pfizer101 recruiting
University of Manitoba103 recruiting
University Health Network, Toronto92 recruiting
McMaster University92 recruiting

Disease activity

Alzheimers92trials
Parkinsons86trials
Depression48trials
Epilepsy36trials
Autism28trials
Stroke26trials
Other Neurology24trials
Adhd23trials
Multiple Sclerosis21trials
Pain Neuropathy18trials

Research institutions

Hôpital Charles-Le MoyneOpenAlexlinked institution
University HospitalOpenAlexlinked institution
Centre de recherche CERVOOpenAlexlinked institution
Celerion (Canada)OpenAlexlinked institution

Clinical evidence trail

NCT07804615A Study to Evaluate the Efficacy, PK, Safety, and Tolerability of VIM0423 in Adults With Parkinson's Disease Tremor Insufficiently Responsive to Dopaminergic TherapyRECRUITING
NCT07762092A Post Authorization Registry Study of Participants Treated With LEQEMBIRECRUITING
NCT07695233Pedunculopontine Nucleus Transcranial Ultrasound Stimulation as a Treatment of Freezing of Gait in Parkinson's DiseaseRECRUITING
NCT07694258Assessment of Safety and Feasibility of FUS Next Generation Dome Helmet (NGDH) to Perform Neuromodulation in Patients With Disorders of ConsciousnessRECRUITING
NCT07671248Tirzepatide in the Treatment of Cannabis Use DisorderNOT_YET_RECRUITING
NCT07567482Exoskeleton-Assisted Mobility in Aging and in Parkinson's DiseaseRECRUITING
NCT07531745ASCEND: Safety and Tolerability of ION337 for the Treatment of Dravet SyndromeRECRUITING
NCT07493265A Study to Evaluate the Efficacy and Safety of E2086 in Adults With NarcolepsyRECRUITING
NCT07477431Levetiracetam for Persons at Risk for Alzheimer's DiseaseRECRUITING
NCT07443293IMPACT 360 for Parkinson's DiseaseACTIVE_NOT_RECRUITING
NCT07434973Stratification and Treatment in Early Psychosis Study - PROMOTENOT_YET_RECRUITING
NCT07424404A Study to Evaluate the Long-term Safety and Tolerability of Xanomeline and Trospium Chloride for the Treatment of Psychiatric Disorders in Children and AdolescentsRECRUITING

Research evidence trail

PUBMEDDetecting dynamic pathways and risk indicators of resilience, vulnerability and stability in normally aging females and males: Integrating data-driven longitudinal and machine learning analyses.2027-01-01
PUBMEDUsing virtual reality to evaluate the difference between pathological and healthy responding to anxiety.2027-01-01
PUBMEDSex differences in the effects of deep brain stimulation on traumatic brain injury-induced cognitive deficits in rats.2027-01-01
PUBMEDThe putative role of the microbiota in the development of neuropsychiatric disorders following early childhood malnutrition.2026-12-31
PUBMEDEpisode-state-associated and shared intrinsic functional network patterns in bipolar disorder.2026-12-15
PUBMEDProtective effects of central leptin on whole-body energy homeostasis following acute olanzapine exposure.2026-12-15
PUBMEDSuicidal ideation at psychiatric emergency presentation predicts trajectories of functional disability and symptom burden in mood and anxiety disorders: A prospective cohort study.2026-12-15
PUBMEDThe effect of vortioxetine on cognitive function in older adults with major depressive disorder: A systematic review.2026-12-15
PUBMEDNationwide Implementation of Newborn Screening for Spinal Muscular Atrophy in Canada.2026-12-01
PUBMEDMenopause and Neurology: Clinical Essentials.2026-12-01
PUBMEDRelations between pregnancy insomnia, relationship conflict, and stress during the COVID-19 pandemic: From pregnancy through early parenthood.2026-12-01
PUBMEDOnabotulinumtoxinA for Painful Foot Dystonia in Parkinson Disease: A Randomized, Double-Blind, Placebo-Controlled Trial.2026-12-01

World Bank context

IT.NET.USER.ZSinternet_users_pct94.4% · 2024
NY.GDP.MKTP.CDgdp_current_usd$2,319.9B · 2025
NY.GDP.PCAP.CDgdp_per_capita_usd$55,698 · 2025
SE.PRM.ENRRschool_enrollment_primary_pct95.01 · 2023
SE.SEC.ENRRschool_enrollment_secondary_pct104.32 · 2023
SH.XPD.CHEX.GD.ZScurrent_health_expenditure_pct_gdp11.3% · 2024
SH.XPD.CHEX.PC.CDcurrent_health_expenditure_per_capita_usd$6,378 · 2024
SH.XPD.GHED.GD.ZSgovernment_health_expenditure_pct_gdp7.9% · 2024
SP.DYN.CBRT.INbirth_rate_crude8.90 · 2024
SP.POP.TOTLpopulation_total41,651,653 · 2025
SP.URB.TOTL.IN.ZSurban_population_pct82.9% · 2025

Macro indicators are shown only where a timestamped World Bank source row exists. Latest collection in this report: 2026-10-24 04:18 UTC. They are context, not NeuroRisk predictions.

Sources and provenance

ClinicalTrials.gov provides NCT evidence. PubMed/NCBI and OpenAlex provide research metadata. OpenAlex links institutions. World Bank indicators are included only when an explicit source row and year exist. NeuroRisk transformations add normalization, ranking and graph connections.

Limitations

Indexed corpus counts are not guaranteed exhaustive global totals. Scores are comparative decision-support signals. This report is not medical advice, regulatory advice, patent clearance, an investment recommendation or a guarantee of outcome.