Enterprise Evidence Report · NR-REPORT-V2.0

Chile
Neuroscience Intelligence

Chile neuroscience evidence report: current clinical, research, institution and source-linked intelligence.

Evidence rank #37 of 50 · Data maturity A · Research score 31.1 · Data confidence 100.0 / 100 · Snapshot 2026-10-29 06:18 UTC.

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68Curated trials
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20Recruiting trials
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23Publications
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20Institutions

Executive interpretation

Chile ranks #37 in the current NeuroRisk evidence-ranked market layer. This ranking summarizes indexed clinical, publication and institution evidence; it is not a probability of commercial success and not an investment recommendation.

Methodology status

Methodology NR-REPORT-V2.0. Clinical metrics and NCT evidence use only records classified as in_scope or related; out_of_scope records remain preserved outside these analytical counts. No synthetic ML confidence is presented as scientific probability. Counts and source links below are tied to the generation snapshot.

Methodology →

Leading sponsors

Merck Sharp & Dohme LLC2412 recruiting
Pfizer50 recruiting
Pontificia Universidad Catolica de Chile40 recruiting
Hoffmann-La Roche30 recruiting
GlaxoSmithKline30 recruiting
Boehringer Ingelheim20 recruiting
Xenon Pharmaceuticals Inc.21 recruiting
Bristol-Myers Squibb11 recruiting
Axovant Sciences Ltd.10 recruiting
Eisai Inc.10 recruiting

Disease activity

Parkinsons27trials
Alzheimers10trials
Epilepsy5trials
Depression5trials
Other Psychiatry3trials
Pain Neuropathy3trials
Anxiety3trials
Schizophrenia2trials
Bipolar Disorder2trials
Stroke2trials

Research institutions

Centro de Recursos Educativos AvanzadosOpenAlexlinked institution
University of ConcepciónOpenAlexlinked institution
Universidad Autónoma de ChileOpenAlexlinked institution
Clínica AlemanaOpenAlexlinked institution
Universidad del DesarrolloOpenAlexlinked institution
Universidad de Los Andes, ChileOpenAlexlinked institution
Hospital Luis Calvo MackennaOpenAlexlinked institution
Instituto de Neurociencia BiomédicaOpenAlexlinked institution

Clinical evidence trail

NCT07875166Effectiveness of Enhanced Dialectical Behavior Therapy Skills Training Group for Borderline Personality DisorderRECRUITING
NCT07753330Efficacy of Expectancy Focused Exposure Therapy for Anxiety DisordersRECRUITING
NCT07611578Dual Tasking Training to Enhance Self-Efficacy in Individuals With Parkinson's DiseaseNOT_YET_RECRUITING
NCT07252739KEYMAKER-U01 Substudy 01J: A Study of Pembrolizumab Plus MK-1084 in Participants With Non-Small Cell Lung Cancer (NSCLC) With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) G12C Mutations (MK-3475-01J/KEYMAKER-U01J)RECRUITING
NCT07221669A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety When Given Before Symptoms Appear in Babies With Genetically Diagnosed Spinal Muscular Atrophy (SMA)RECRUITING
NCT07216703A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) as First-line Maintenance Treatment of Cervical Cancer (MK-2870-036/TroFuse-036/GOG-3123/ENGOT-cx22)RECRUITING
NCT06976216A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's DiseaseRECRUITING
NCT06966700A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)RECRUITING
NCT06952504A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)RECRUITING
NCT06788912Pembrolizumab (MK-3475) Plus Investigational Agents in Resectable Non-small Cell Lung Cancer (NSCLC) (MK-3475-01E/KEYMAKER-U01)RECRUITING
NCT06780085A Study of Investigational Agents in Participants With Previously Treated Stage IV Nonsquamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01H/KEYMAKER-U01)RECRUITING
NCT06504394A Study to Evaluate the Safety and Efficacy of Pembrolizumab (MK-3475) Coformulated With Berahyaluronidase Alfa (MK-3475A) in Participants With Relapsed or Refractory Classical Hodgkin Lymphoma (rrcHL) or Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma (rrPMBCL)(MK-3475A-F65)ACTIVE_NOT_RECRUITING

Research evidence trail

PUBMEDMetformin enhances hippocampal excitatory synaptic transmission and preserves synaptic plasticity under amyloid-β oligomer-induced dysfunction.2026-11-15
PUBMEDClinical and audiovestibular findings in pediatric vestibular migraine spectrum disorders.2026-11-01
PUBMEDPressure Points: A Scoping Review of Intracranial Pressure and Mean Arterial Pressure Measurement and Reporting Practices in Neurocritical Care.2026-10-09
PUBMEDAcute Effects of Automated Peripheral Stimulation on Autonomic and Functional Capacity in Parkinson's Disease.2026-10-09
PUBMEDComparative analysis of the effects of Δ9-tetrahydrocannabinol and cannabidiol on pilocarpine-induced status epilepticus in mice.2026-10-06
PUBMEDSpeech clocks decode dementia phenotypes, social exposome, and biological aging.2026-10-02
PUBMEDDo Latino Populations Have a Distinct Pain Sensitivity? A Quantitative Sensory Testing Study in Chilean Healthy Volunteers.2026-10-01
PUBMEDSelective impairment of long-term depression in accumbal D1R+ MSNs involves calcium-permeable AMPARs in early Alzheimer's disease.2026-10-01
PUBMEDPotential adverse effects of antipsychotics during pregnancy: A narrative review with a focus on metabolic alterations.2026-10-01
PUBMEDDrosophila melanogaster as a Model for Autism Spectrum Disorder: Insights into Lifelong Neuronal Vulnerability.2026-09-12
PUBMEDImpaired skin reinnervation in epidermolysis bullosa due to neurotrophic deficiency.2026-08-01
PUBMEDExercise preconditioning attenuates ischemic neurological deficits without modulating motor learning in a rodent model of focal cortical ischemia.2026-08-01

World Bank context

IT.NET.USER.ZSinternet_users_pct95.6% · 2024
NY.GDP.MKTP.CDgdp_current_usd$357.4B · 2025
NY.GDP.PCAP.CDgdp_per_capita_usd$17,995 · 2025
SE.PRM.ENRRschool_enrollment_primary_pct99.49 · 2024
SE.SEC.ENRRschool_enrollment_secondary_pct105.61 · 2024
SH.XPD.CHEX.GD.ZScurrent_health_expenditure_pct_gdp10.5% · 2024
SH.XPD.CHEX.PC.CDcurrent_health_expenditure_per_capita_usd$1,760 · 2024
SH.XPD.GHED.GD.ZSgovernment_health_expenditure_pct_gdp5.1% · 2024
SP.DYN.CBRT.INbirth_rate_crude8.72 · 2024
SP.POP.TOTLpopulation_total19,859,921 · 2025
SP.URB.TOTL.IN.ZSurban_population_pct89.2% · 2025

Macro indicators are shown only where a timestamped World Bank source row exists. Latest collection in this report: 2026-10-24 04:18 UTC. They are context, not NeuroRisk predictions.

Sources and provenance

ClinicalTrials.gov provides NCT evidence. PubMed/NCBI and OpenAlex provide research metadata. OpenAlex links institutions. World Bank indicators are included only when an explicit source row and year exist. NeuroRisk transformations add normalization, ranking and graph connections.

Limitations

Indexed corpus counts are not guaranteed exhaustive global totals. Scores are comparative decision-support signals. This report is not medical advice, regulatory advice, patent clearance, an investment recommendation or a guarantee of outcome.