Enterprise Evidence Report · NR-REPORT-V2.0

Japan
Neuroscience Intelligence

Japan neuroscience evidence report: current clinical, research, institution and source-linked intelligence.

Evidence rank #11 of 50 · Data maturity A · Research score 43.6 · Data confidence 100.0 / 100 · Snapshot 2026-10-29 06:18 UTC.

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182Curated trials
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51Recruiting trials
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367Publications
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276Institutions

Executive interpretation

Japan ranks #11 in the current NeuroRisk evidence-ranked market layer. This ranking summarizes indexed clinical, publication and institution evidence; it is not a probability of commercial success and not an investment recommendation.

Methodology status

Methodology NR-REPORT-V2.0. Clinical metrics and NCT evidence use only records classified as in_scope or related; out_of_scope records remain preserved outside these analytical counts. No synthetic ML confidence is presented as scientific probability. Counts and source links below are tied to the generation snapshot.

Methodology →

Leading sponsors

Merck Sharp & Dohme LLC2211 recruiting
Eli Lilly and Company155 recruiting
Hoffmann-La Roche102 recruiting
Eisai Co., Ltd.91 recruiting
Takeda70 recruiting
Biogen62 recruiting
GlaxoSmithKline60 recruiting
AbbVie51 recruiting
Boehringer Ingelheim50 recruiting
Eisai Inc.44 recruiting

Disease activity

Parkinsons42trials
Alzheimers38trials
Epilepsy24trials
Neuromuscular12trials
Depression10trials
Schizophrenia7trials
Stroke6trials
Other Neurology5trials
Adhd4trials
Migraine Headache4trials

Research institutions

Takeda (Japan)OpenAlexlinked institution
Yamaguchi UniversityOpenAlexlinked institution
Utano HospitalOpenAlexlinked institution
Tottori UniversityOpenAlexlinked institution
Akita UniversityOpenAlexlinked institution
National Institutes of Natural SciencesOpenAlexlinked institution
Chugai Pharmaceutical Co., Ltd. (Japan)OpenAlexlinked institution
Chiba Cancer CenterOpenAlexlinked institution

Clinical evidence trail

NCT07666022A Clinical Study to Evaluate the Safety of MF1, a New Treatment for Parkinson's Disease-related Disorders (MF1 Study)RECRUITING
NCT07589595A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)RECRUITING
NCT07493265A Study to Evaluate the Efficacy and Safety of E2086 in Adults With NarcolepsyRECRUITING
NCT07446894MSA-01 in Multiple System AtrophyRECRUITING
NCT07424404A Study to Evaluate the Long-term Safety and Tolerability of Xanomeline and Trospium Chloride for the Treatment of Psychiatric Disorders in Children and AdolescentsRECRUITING
NCT07410507A Study of Brenipatide in Adult Participants With SchizophreniaRECRUITING
NCT07291453Loving Habits: A Feasibility Study of a Support Program for Building New Parent-child Behavioral HabitsRECRUITING
NCT07227857A First-in-human Study of S230815 in Pediatric Participants With KCNT1-related Developmental and Epileptic EncephalopathyRECRUITING
NCT07221669A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety When Given Before Symptoms Appear in Babies With Genetically Diagnosed Spinal Muscular Atrophy (SMA)RECRUITING
NCT07216703A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) as First-line Maintenance Treatment of Cervical Cancer (MK-2870-036/TroFuse-036/GOG-3123/ENGOT-cx22)RECRUITING
NCT07170150A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's DiseaseRECRUITING
NCT07142954Epidemiology and Biomarker Study in Alzheimer's DiseaseRECRUITING

Research evidence trail

PUBMEDEstablishment of age- and sex-stratified normative data for the Brief Assessment of Cognition (BAC) app in healthy Japanese individuals.2027-01-01
PUBMEDHeterogeneous vascular contributions to cognitive impairment and dementia.2027-01-01
PUBMEDAmyloid-β aggregation inhibitory activity and neuroprotective effects of metabolites of Trichoderma pluripenicillatum.2027-01-01
PUBMEDBacterial constipation: Mucin-degrading intestinal commensal bacteria cause constipation.2026-12-31
PUBMEDBase editing rescues a hereditary motor neuron disease in mouse and patient-derived iPSC organoid models.2026-12-10
PUBMEDLongitudinal NODDI-DTI assessment of brain recovery following CPAP in obstructive sleep apnea: Tissue-compartment changes in white and gray matter.2026-12-01
PUBMEDM3 muscarinic receptor antagonism attenuates cocaine-induced hippocampal oligodendroglial changes and relapse-like behavior in male mice.2026-12-01
PUBMEDLongitudinal mother-rated screening of male partners' depressive symptoms using the Edinburgh postnatal depression scale during the perinatal period.2026-12-01
PUBMEDBeyond executive dysfunction: The precuneus as an introspective monitoring hub for driving safety.2026-12-01
PUBMEDDigital behavior therapy for insomnia in the general population: secondary analysis of the multi-arm RESiLIENT trial with active comparators.2026-12-01
PUBMEDAutistic-like traits and longitudinal changes in health-related quality of life among individuals with bipolar disorder: A 12-month study.2026-12-01
PUBMEDChronotype and insomnia symptoms in the incidence and persistence of depressive symptoms: An 8-year longitudinal cohort study.2026-12-01

World Bank context

IT.NET.USER.ZSinternet_users_pct85.5% · 2024
NY.GDP.MKTP.CDgdp_current_usd$4,435.2B · 2025
NY.GDP.PCAP.CDgdp_per_capita_usd$35,951 · 2025
SE.PRM.ENRRschool_enrollment_primary_pct101.13 · 2023
SE.SEC.ENRRschool_enrollment_secondary_pct101.54 · 2023
SH.XPD.CHEX.GD.ZScurrent_health_expenditure_pct_gdp10.7% · 2023
SH.XPD.CHEX.PC.CDcurrent_health_expenditure_per_capita_usd$3,638 · 2023
SH.XPD.GHED.GD.ZSgovernment_health_expenditure_pct_gdp9.1% · 2023
SP.DYN.CBRT.INbirth_rate_crude5.70 · 2024
SP.POP.TOTLpopulation_total123,366,734 · 2025
SP.URB.TOTL.IN.ZSurban_population_pct92.3% · 2025

Macro indicators are shown only where a timestamped World Bank source row exists. Latest collection in this report: 2026-10-24 04:18 UTC. They are context, not NeuroRisk predictions.

Sources and provenance

ClinicalTrials.gov provides NCT evidence. PubMed/NCBI and OpenAlex provide research metadata. OpenAlex links institutions. World Bank indicators are included only when an explicit source row and year exist. NeuroRisk transformations add normalization, ranking and graph connections.

Limitations

Indexed corpus counts are not guaranteed exhaustive global totals. Scores are comparative decision-support signals. This report is not medical advice, regulatory advice, patent clearance, an investment recommendation or a guarantee of outcome.